EXCLUSIVE: Health Canada Official Deleted Scientist’s Note Saying mRNA Shots Have
‘High Level of Impurity’: Internal Emails
The assessment was meant as a brief on recent findings about the creation of unintended proteins by mRNA COVID-19 vaccines.
Two senior Health Canada (HC) officials, including the one with final authority on vaccine authorization, expressed concerns about the conclusions written by the HC scientist tasked with producing the assessment.
“I am very wary of the 4th bullet on impurities that Dr. [Agnes] Klein had put in,” HC Senior Advisor Poovadan Anoop wrote in a Dec. 14, 2023, email referring to the internal HC assessment written by Dr. Agnes V. Klein, a senior medical advisor with HC. Mr. Anoop’s email was addressed to his superior, Sophie Sommerer, director general of Health Canada’s Biologic and Radiopharmaceutical Drugs Directorate (BRDD). The unit is responsible for approving vaccines.
The Epoch Times obtained the internal records through the access to information system.
The assessment had noted about 8 percent of the proteins produced by the mRNA shots were unintended or “frameshifted” proteins capable of evoking an immune response. Dr. Klein called it a “high level of impurity.”
“Does this mean with the impurity levels caused by frameshift, the vaccines would not pass muster, notwithstanding the fact that the translated proteins are not harmful,” Mr. Anoop asked in his email. He later told his superior that he “struck out” a paragraph drawn from the original assessment mentioning the “high level of impurity.”
The lengthy scientific Substack post discussed the initial frameshifting discovery reported in the journal Nature on Dec. 6. Scientists found that the mRNA injections, which give instructions to the cells to create the SARS-CoV-2 virus’ spike protein to generate an immune response, also produce other unintended, or frameshifted proteins that are capable of evoking an immune response.
The researchers estimated that approximately 8 percent of the proteins generated by the mRNA shots are frameshifted.
‘High Level of Impurity’
“If one were to consider this as an impurity during manufacturing or part of an impurity that can develop during the uptake and metabolism of a drug, which does happen in other instances, one would have to consider this as a high level of impurity,” she wrote.
Dr. Klein added that impurities and metabolic deviations usually do not exceed 1 or 2 percent. In the event those levels are higher, this “must be investigated and justified,” she said.
“The fact that the frameshift does not exist with a DNA vaccine, may speak in favour of DNA vaccines and, overall maybe, against mRNA vaccines,” she added.
Despite raising those concerns, Dr. Klein said in the email containing her assessment to the senior officials that there is “nothing to worry about in this regard.”
‘Made Changes’
“I read the Science article for my own interest and have made changes in this summary (as opposed to the report provided by Dr. Klein) to make the message clear,” Mr. Anoop wrote above a bullet-point form summary drawn from Dr. Klein’s assessment. The Science article plays down concerns and is titled “mRNA vaccines may make unintended proteins, but there’s no evidence of harm.” It asserts in its opening that COVID-19 vaccines “saved millions of lives.”
According to his LinkedIn profile, Mr. Anoop has a master’s in microbiology and biotechnology, and his government experience is in risk management and compliance.
“I’m a little concerned about the overall conclusions below re. concern about manufacturing and impurities of mRNA vaccines,” she wrote without elaborating. She then tasked Mr. Anoop to check whether Dr. Sean Li, a Health Canada research scientist, had commented on the conclusion.
Ms. Sommerer also asked whether the BRDD had “standard lines” on whether or how it considers articles in scientific literature. She then wrote: “We need to remind everyone that the company is expected to monitor the safety of their vaccines and report to HC if they identify any potential signals.” The “company” refers to vaccine manufacturers.
After receiving Ms. Sommerer’s email expressing discontent with Dr. Klein’s conclusion, Mr. Anoop told another senior Health Canada official that he had “dumbed down” Dr. Klein’s input and also flagged Ms. Sommerer’s comments expressing her dissatisfaction with it.
Mr. Anoop then emailed Dr. Michael Rosu-Myles, the director of the Health Canada’s Centre for Oncology, Radiopharmaceuticals and Research. “I know you also have a line on how we consider literature articles – we need to say that we consider only those articles that are under the scope of review and regulatory requirements,” Mr. Anoop said, suggesting the issues about frameshifting fall outside the literature that Health Canada typically considers in its regulatory role.
‘Less Optimal’
“Apparently, the mRNA vaccines had generated a just bit [sic] more than the cells could mop out,” the research scientist said, adding there is “no evidence” suggesting that the antibodies resulting from the frameshift are harmful.
Dr. Li also commented on the 8 percent frameshifting figure, saying that if the figure were independently confirmed, it would “likely be thought as being less optimal.”
‘Struck Out’
“I struck out a bullet as that seems to be leaping to a pronouncement when you consider what Michael [Dr. Rosu-Myles] indicates in his/Sean Li’s assessment,” wrote Mr. Anoop.
The struck-out paragraph is the one taken from Dr. Klein’s assessment mentioning the “high level of impurity.”
Notably, the summary produced by Mr. Anoop also does not contain the concerns raised by Dr. Li about mRNA conformity issues and the “relatively high level of frameshift.”
The summary concludes by saying that vaccine makers are expected to monitor their products and report safety signals to HC. It says the department has “sufficient processes in place to evaluate product risk prior to authorization” and to “continue to identify safety issues that may arise post-authorization.”
The final assessment sent to Chief Medical Advisor Sharma was not included in the records obtained via access to information. The Epoch Times asked Health Canada that it be provided and also asked whether Pfizer-BioNTech and Moderna were contacted to discuss the frameshifting issue. A response was not obtained by publication time.
Autoimmunity
“This is NOT about ‘antibodies being harmful,’” she said. “This is about unforeseen, inappropriate induction of potent immune responses that can lead to autoimmune conditions that can be life-altering at best, and life-threatening at worst.”
Dr. David Wiseman, the lead author of the paper, expressed concerns about what Health Canada is doing about the issue. “What efforts is HC doing to identify and characterize the frameshift proteins and to determine their toxicity?” he said in an email to The Epoch Times.
Meanwhile, Dr. Philip Oldfield, who has over three decades of experience specializing in the bioanalysis of protein/nucleic acid therapeutics and regulatory affairs, told The Epoch Times in an interview that he “totally agrees” with HC scientist Dr. Klein’s assessment that 8 percent frameshifting is a high level of impurity. But he counterpointed that the rest of the 92 percent, which is the SARS-CoV-2 spike protein, “does most of the damage.”
In a study published last year in European Review for Medical and Pharmacological Sciences, Italian scientists noted finding the viral spike protein in the blood serum of patients two months after vaccination.
After looking at the internal HC records on frameshifting, Dr. Oldfied said he noted a “lack of objectivity” and a deliberate attempt to “play it down.”
“They basically tried to find as much information in order to debunk the fact that it might be serious,” he says. “It doesn’t give me confidence that they’re there to make us safe.”
Please correct me if I am wrong in this analysis: mRNA vaccines were discovered long before they were ever used for anything, long before Covid_19 exploded on the earth. The serious flaws in mRNA vaccines meant that it could never pass clinical testing which is extremely expensive to begin with.
After Covid_19 spread across the world, mRNA vaccines suddenly appeared as the remedy, and because the pandemic was an emergency, it didn't have to pass clinical trials as long as there was no other vaccine available to treat Covid. That's why Ivermectin and Hydroxychloroquine had to be attacked so violently and at the cost of so many lives. Had they been able to prove their effectiveness, m/RNA vaccines would never have been approved and Big Pharma would be out trillions of dollars.
So, being a conspiracy theorist, I naturally wonder whether the pharmaceutical companies that had invented mRNA vaccines had something to do with the release of Covid_19 in Wuhan.
What do you think, am I far-out in left field?
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